A curve for each animal
Many methods need a separate group of animals for each time point, because the measurement ends the experiment or is too stressful to repeat. A scan that is quick, needs no anaesthesia and uses no radiation can be repeated every week. Every animal then delivers its own curve, and a change is seen against the animal's own starting point.
Where it is used
- Diet-induced obesity and the effect of diet composition
- Genetic models of obesity and metabolic disease
- Ageing and exercise studies
- Nutritional interventions and energy-metabolism studies
- Tumour growth in obese and lean animals
Cleaner data from fewer animals
Each animal acts as its own control, so the differences between individuals no longer hide the effect being studied. This usually allows smaller groups for the same statistical power, which is a practical contribution to reducing the number of animals used.
Points that matter in practice
- Keep the conditions of each scan the same: the time of day, the fasting state and the handling
- Habituate the animals to the holder, so that repeated scanning does not itself become a stress
- Keep the calibration consistent over the whole study, with regular checks, so that changes are those of the animals
- Plan the schedule with the number of scans per day that one operator can run
- For research use only
From your study design to a routine
Describe your models and your study plan. MSY Consulting helps you plan the scanning schedule, the calibration and the procedures, and trains the people who will run the scans.
Let's talk about your application
Send an email describing your instrument and your application, and you will get a reply.
contact@msyconsulting.euMSY CONSULTING SAS · Wissembourg, France · LinkedIn