Three different stories in lean mass
Juvenile animals build lean mass quickly. Healthy ageing brings a slow decline. A wasting or cachexia model brings a steep loss of lean tissue, often together with the loss of fat. Reading lean mass directly, and repeatedly, tells these stories apart and shows when an intervention changes them.
Where it is used
- Cachexia models, including those linked to cancer
- Muscle-wasting and sarcopenia models
- Growth studies in juvenile animals
- Ageing studies and tests of treatments that preserve muscle
The whole composition over time
In a wasting model, the picture is more than a loss of weight. Lean mass falls, fat is used up, and free fluid can rise. Reading all three separately shows what the loss really consists of.
What it adds
- The same animals can be followed through the whole course of the model
- No anaesthesia, which matters in weak animals
- No radiation, so repeated scans are possible
- Lean mass and free fluid are read separately, which a scale cannot do
Points that matter in practice
- In animals with a tumour, the mass of the tumour can influence the reading, so interpret the lean mass together with the tumour burden
- Very small juvenile animals need a holder that fits and a calibration that covers their size
- Weak animals need gentle handling and short sessions
- For research use only
From your model to a routine
Describe your models and your questions. MSY Consulting helps you plan the calibration and the scanning schedule for your animals, and trains the people who will run the scans.
Let's talk about your application
Send an email describing your instrument and your application, and you will get a reply.
contact@msyconsulting.euMSY CONSULTING SAS · Wissembourg, France · LinkedIn